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1 week ago | 
genengnews.com | Corinna Singleman |Alex Philippidis |Uduak Grace Thomas |Fay Y. Lin
Credit: Just_Super / iStock / Getty Images Plus
BIO 2025 is off and running. GEN editors discuss the size and scope of the bustling conference hall and share excitement about the week’s talks and panels. News from BIO includes the announcement of Lilly’s acquisition of Verve Therapeutics. Editors discuss the implications of industry-backed therapeutics amid cautious investors and public sentiment.
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1 week ago | 
genengnews.com | Corinna Singleman
Credit: Miyako Nakamura / iStock / Getty Images Plus
The proteins found in nature represent only a tiny fraction of the nearly limitless protein structures that could theoretically exist. By designing proteins de novo—from scratch—scientists can more efficiently create novel therapeutics tailored for specific biological functions. In a new study, researchers introduce an AI-driven framework that accelerates this process, moving protein design toward custom therapeutics and precision medicine.
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2 weeks ago | 
genengnews.com | Corinna Singleman
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Vaccinations have revolutionized healthcare, but designing them remains complex, requiring time and creativity, especially for vaccines against viruses, which are difficult to study.
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3 weeks ago | 
genengnews.com | Alex Philippidis |Fay Y. Lin |Uduak Grace Thomas |Corinna Singleman
A gene therapy clinical trial for Danon disease run by Rocket Pharmaceuticals has been suspended following the death of a patient. MIT and Recursion have released Boltz-2, an open-source tool that predicts molecular binding affinity at newfound speed and accuracy, aiming to democratize commercial drug discovery. Intellia Therapeutics saw its stock nosedive late last week after a patient in its Phase III trial of the CRISPR-based therapy experienced non-lethal liver toxicity.
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3 weeks ago | 
genengnews.com | Corinna Singleman
If you have ever experienced a cold sore, you may be one of the estimated 3.8 billion people worldwide (64%) who are infected with herpes simplex virus type 1 (HSV-1). Though the majority of people experience no or mild symptoms, HSV-1 has the ability to cause a rare, life-threatening neurological condition called HSV-1 encephalitis.
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1 month ago | 
genengnews.com | Corinna Singleman
Home Topics Cancer More Mutations in Childhood Cancer Might Mean More Therapy Options Characteristic histology of a newborn Wilms tumor driven by a FOXR2 mutation. [Ronald de Krijger / Princess Máxima Center for Pediatric Oncology] Characteristic histology of a newborn Wilms tumor driven by a FOXR2 mutation. [Ronald de Krijger / Princess Máxima Center for Pediatric Oncology]
Childhood cancers are often considered genetically simple, containing few mutations.
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1 month ago | 
genengnews.com | Fay Y. Lin |Uduak Grace Thomas |Alex Philippidis |Corinna Singleman
Home Topics Genome Editing Customized CRISPR for KJ, 10x and Illumina Lawsuits, Regeneron Bags 23andMe Scientists analyzing DNA helix and editing genome within organisms, CRISPR technology Credit: elenabs/ 1189916170/iStock / Getty Images Plus
A baby, named KJ, has become the first patient to be treated with a personalized CRISPR therapy to address a severe metabolic disorder.
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1 month ago | 
genengnews.com | Corinna Singleman
Home Topics Coronavirus New Multi-Species Bat Organoid Platform Enhances Pandemic Preparedness Bats flying over cave entrance. Credit: Stijn Dijkstra / EyeEm / Getty Images
The world’s largest bat organoid platform, which promises improvement in the study of zoonotic viruses, has been newly developed by scientists at the Institute for Basic Science (IBS) in Korea.
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1 month ago | 
genengnews.com | Uduak Grace Thomas |Julianna LeMieux |Alex Philippidis |Corinna Singleman
Home Topics Cancer COVID-19’s Origin Insights, Recursion Reverses Course, and AACR Stands Up for Cancer... T-cells attacking cancer cell illustration of microscopic photos. [Peddalanka Ramesh Babu/Getty Images] Credit: Peddalanka Ramesh Babu/Getty Images
The exact origins of SARS-CoV-2 are still something of a mystery, but scientists may be one step closer. This week, we discuss research that points to a possible explanation for how the virus reached Wuhan.
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1 month ago | 
genengnews.com | Corinna Singleman
Home Topics Coronavirus SARS-CoV-2 Likely Spread Through Wildlife Trade, Not Bat Migration Greater horseshoe bat (Rhinolophus ferrumequinum) in flight at night, Luxembourg - stock photo Credit: Marko Konig/Getty Images
Since the start of the COVID-19 pandemic, there has been controversy surrounding the origins of SARS-CoV-2.
