Genetic Engineering & Biotechnology News

Since its inception in 1981, Genetic Engineering & Biotechnology News (GEN) has established itself as the leading publication in the biotech field. GEN offers a print edition 21 times each year, along with a wealth of exclusive online content that includes news updates, in-depth analysis, webinars, videos, and surveys. The publication's distinct emphasis on news and technology spans the full bioproduct life cycle, covering areas such as drug discovery, initial research and development, applied research (like omics, biomarkers, and diagnostics), bioprocessing, and the commercialization process.

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WuXi Biologics Reports Completion of First Commercial PPQ Campaign at 15,000 L Production Line

6 days ago | genengnews.com | John Sterling

Home Topics Bioprocessing WuXi Biologics Reports Completion of First Commercial PPQ Campaign at 15,000 L... Credit: WuXi Biologics Credit: WuXi Biologics WuXi Biologics completed the first commercial project Process Performance Qualification (PPQ) campaign for its three sets of 5,000 L single-use bioreactors (SUBs) in the second drug substance line of its MFG20 facility at the Hangzhou site in China.
Bypassing Size Constraints, Scientists Use CD36 Protein to Deliver Bulky PROTACs

6 days ago | genengnews.com | Uduak Grace Thomas

Home Topics Cancer Bypassing Size Constraints, Scientists Use CD36 Protein to Deliver Bulky PROTACs Proteasome collaborate with ubiquitin to degrade proteins. [Love Employee/Getty Images] Proteasome collaborate with ubiquitin to degrade proteins.
Distinct Dendrites, Distinct Rules for Learning in a Single Neuron Mouse Study

1 week ago | genengnews.com | Sophia Ktori

Home News Distinct Dendrites, Distinct Rules for Learning in a Single Neuron Mouse Study Neurons and their branch extensions known as dendrites are featured within a mouse’s cerebral cortex. [Komiyama Lab, UC San Diego] Neurons and their branch extensions known as dendrites are featured within a mouse’s cerebral cortex. [Komiyama Lab, UC San Diego] How do we learn something new?
After Job Cuts, "We're Entering a Very New Territory for Biotech"

1 week ago | genengnews.com | Alex Philippidis

The old saw, “You can’t tell the players without a scorecard,” is an especially fitting way of describing the effect of the overhaul in progress at the U.S. Department of Health and Human Services (HHS) and the agencies it oversees that regulate biopharma—especially the FDA, the NIH, and the U.S. Centers for Disease Control and Prevention (CDC). Earlier this month, HHS began eliminating some 10,000 jobs as announced in late March by HHS Secretary Robert F.
Multi-Zonal Liver Organoids Replicate Human Organs, Improve Injury Survival in Rodents

1 week ago | genengnews.com | Uduak Grace Thomas

Scientists from Cincinnati Children’s Hospital Medical Center and their collaborators have used human stem cells to develop liver organoids that faithfully replicate key zones observed in human livers. Furthermore, when the organoids were transplanted into immunodeficient rats whose liver-bile duct systems had been disconnected, their survival rates nearly doubled.
Brain Regions Essential for Logical Thinking and Problem Solving in Humans Identified

1 week ago | genengnews.com | Sophia Ktori

Using two newly developed types of reasoning tests, a team of researchers at UCL and UCLH has identified key brain regions that are essential for logical thinking and problem-solving. The results will help to increase our understanding of how the human brain supports reasoning skills that enable us to comprehend, draw conclusions, and deal with new and novel problems.
Gene Syntax Guidelines to Increase Expression and Predictability

1 week ago | genengnews.com | Gail Dutton

Sizeable differences in gene expression means and ratios—based solely upon where genes are located on a plasmid (gene syntax)—have been discovered by researchers at Dartmouth College. This new understanding will help biomanufacturers to design more effective plasmids and genetic circuits and thereby enable more precise measurements of promoter activity, more accurate gene expression, and more predictable engineered systems.
Circulating Tumor DNA Test May Help Predict Melanoma Recurrence

1 week ago | genengnews.com | Sophia Ktori

Home Topics Cancer Circulating Tumor DNA Test May Help Predict Melanoma Recurrence Melanoma [Callista Images/Getty Images] Melanoma [Callista Images/Getty Images] A study led by scientists at NYU Langone Health and its Perlmutter Cancer Center has shown that monitoring blood levels of DNA fragments shed by dying tumor cells may accurately predict skin cancer recurrence.
Cyprumed and MSD Agree to Develop Oral Peptide Formulations and CDMO Meribel Pharma Solutions Launches

1 week ago | genengnews.com | John Sterling

Home Topics Bioprocessing Cyprumed and MSD Agree to Develop Oral Peptide Formulations and CDMO Meribel... Credit: Sean Anthony Eddy/Getty Images Credit: Sean Anthony Eddy/Getty Images Cyprumed and MSD signed a nonexclusive license and option agreement to develop oral formulations of MSD’s peptides using Cyprumed’s innovative drug delivery technology. MSD gains nonexclusive global rights to Cyprumed’s oral peptide delivery platform for an undisclosed number of targets.
Attovia Building Immune-Mediated Disease Pipeline with $90M Series C

1 week ago | genengnews.com | Alex Philippidis

Home Topics Drug Discovery Attovia Building Immune-Mediated Disease Pipeline with $90M Series C Credit: Love Employee/Getty Images Credit: Love Employee/Getty Images Attovia Therapeutics CEO Tao Fu Attovia Therapeutics has completed an oversubscribed $90 million Series C financing, which the company plans to use along with existing cash and investments to advance its two lead pipeline candidates through clinical proof-of-concept, as well as expand its pipeline of treatments for...