Genetic Engineering & Biotechnology News

Since its inception in 1981, Genetic Engineering & Biotechnology News (GEN) has established itself as the leading publication in the biotech field. GEN offers a print edition 21 times each year, along with a wealth of exclusive online content that includes news updates, in-depth analysis, webinars, videos, and surveys. The publication's distinct emphasis on news and technology spans the full bioproduct life cycle, covering areas such as drug discovery, initial research and development, applied research (like omics, biomarkers, and diagnostics), bioprocessing, and the commercialization process.

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Intercellular Fluid Flow Impacts Tissue Response to Physical Forces

1 week ago | genengnews.com | Sophia Ktori

These images use color markers—blue for nuclei, red for cell membranes, and green for fluid—to show that spaces between cells shrink as fluid moves out during tissue compression, from left to right and top to bottom. [Courtesy of Ming Guo, Fan Liu, et al] Water makes up around 60% of the human body. More than half of this water is inside the cells that make up organs and tissues, and much of the remaining water flows in the spaces between cells.
US Pharmacopeia Recognizes Mass Photometry in New AAV Reference Standards for Gene Therapy Quality

1 week ago | genengnews.com | John Sterling

The SamuxMP mass photometer for AAV analytics is used for characterizing the US Pharmacopeia’s new adeno-associated virus (AAV) reference standards. [Refeyn] The U.S. Pharmacopeia (USP) has recognized mass photometry as a key orthogonal method for characterizing its new adeno-associated virus (AAV) reference standards, as referenced in the draft general chapter <1067>, according to Refeyn.
BIO 2025, Huge Virtual Cell Dataset, AI-Designed De Novo Proteins

1 week ago | genengnews.com | Corinna Singleman |Alex Philippidis |Uduak Grace Thomas |Fay Y. Lin

Credit: Just_Super / iStock / Getty Images Plus BIO 2025 is off and running. GEN editors discuss the size and scope of the bustling conference hall and share excitement about the week’s talks and panels. News from BIO includes the announcement of Lilly’s acquisition of Verve Therapeutics. Editors discuss the implications of industry-backed therapeutics amid cautious investors and public sentiment.
At BIO, Companies Launch New Products for AAV Manufacturing, AI Drug Discovery

1 week ago | genengnews.com | Uduak Grace Thomas

A view of some of the exhibitors in attendance at BIO 2025 [Uduak Thomas] At this year’s BIO International Convention, held June 16–19 in Boston, MA, two companies, 64x Bio and Fauna Bio, introduced new products aimed at improving therapy delivery and identifying novel drug targets for a range of human diseases, respectively. For its part, 64x Bio launched AAV Apex suite, a product designed to address bottlenecks in gene therapy manufacturing.
King Faisal Specialist Hospital & Research Center and Germfree Labs Agree to Develop Advanced Therapy Manufacturing Campus in Riyadh

1 week ago | genengnews.com | John Sterling

Credit: Reptile8488/Getty Images The King Faisal Specialist Hospital & Research Center (KFSHRC) and Germfree Laboratories agreed to partner to develop Saudi Arabia’s first fully integrated, modular advanced therapy Medicinal product (ATMP) manufacturing campus.
Nanoparticle Drug Delivery System Improves Stability and Drug Loading

1 week ago | genengnews.com | Sophia Ktori

Credit: Frame Studio / Getty Images Scientists at Xi’an Jiaotong-Liverpool University (XJTLU) and at Nanjing University have combined a widely used medical polymer with a natural blood protein to develop a new nanoparticle drug delivery system that the team says can carry much larger amounts of disease-fighting drugs and remain stable much longer than current nanoparticle systems.
Bionova Scientific Expands Capacity and Joins Advanced Therapies Market

1 week ago | genengnews.com | John Sterling

FlexFactory [Cytiva] Bionova Scientific, a CDMO, is entering the advanced therapy manufacturing space by installing its third FlexFactory manufacturing platform while maintaining their core monoclonal antibody (mAb) business. Bionova will also use Cytiva’s Fast Trak process development services to help advance their entry into genomic medicines.
QurAlis Opens New Global Headquarters

1 week ago | genengnews.com | John Sterling

Credit: QurAlis QurAlis opened its new global corporate headquarters in Cambridge, MA. The company’s new 30,000-sq-ft research facility and office space, located at 35 Cambridgepark, doubles QurAlis’ footprint in Alewife Biotech Park. “Maintaining our corporate headquarters in Cambridge positions us at the heart of a thriving biotechnology hub with world-class talent and leading research institutions,” said Jason Brown, CFO.
Barcelona’s Blood and Tissue Bank Looks to Improve Cell Therapy Cost Effectiveness

1 week ago | genengnews.com | Vivienne Raper

CAR T-cells attack cancer cell, 3D illustration. [Nemes Laszlo/Getty Images] Barcelona’s blood and tissue bank, Banc de Sang i Teixits, reports that it has developed a new system for the large-scale production of mesenchymal stromal cells (MSCs). The team says they’ve validated a stirred-tank bioreactor system they hope will help supply hospitals with cheaper treatments for conditions including myocardial infraction and spinal cord injury.
Integrative Exome Sequencing and Machine Learning Identify New Genes Contributing to Systemic Sclerosis Risk

1 week ago | genengnews.com | John Sterling

Diagnostic test for systemic sclerosis. [Cesare Ferrari/Getty Images] Scientists at the Baylor College of Medicine and collaborating institutions used complementary approaches that integrate exome sequencing and evolutionary action machine learning to identify protein changes and their associated mechanisms in systemic sclerosis (SSc), a severe autoimmune disease with complex genetic causes.