Uduak Grace Thomas

1 day ago | genengnews.com | Alex Philippidis |Fay Y. Lin |Uduak Grace Thomas |Corinna Singleman

A gene therapy clinical trial for Danon disease run by Rocket Pharmaceuticals has been suspended following the death of a patient. MIT and Recursion have released Boltz-2, an open-source tool that predicts molecular binding affinity at newfound speed and accuracy, aiming to democratize commercial drug discovery. Intellia Therapeutics saw its stock nosedive late last week after a patient in its Phase III trial of the CRISPR-based therapy experienced non-lethal liver toxicity.

1 day ago | genengnews.com | Uduak Grace Thomas

Scientists from the University of California, San Diego (UC San Diego), have published data from a study that tested the effects of a gene therapy for Alzheimer’s disease (AD) dubbed AAV9-Synapsin-promoted Cav-1 (SynCav1) in mice. The results indicate that the therapy could be an effective way to protect the brain from disease-related damage and preserve cognitive function.

2 days ago | genengnews.com | Uduak Grace Thomas

Stanford University researchers are using machine learning algorithms to modify human proteins with an eye toward improving the efficacy and safety of targeted cell and gene therapies by reducing the risks of an adverse immune response.

4 days ago | genengnews.com | Uduak Grace Thomas

Home News Diminished Stress Response in Aging Neurons Linked to Neurodegeneration Credit: cherezoff / iStock / Getty Images Plus Credit: cherezoff / iStock / Getty Images Plus As people age, their risk of developing neurodegenerative disorders like dementia, Alzheimer’s disease, and Parkinson’s disease increases. A new study from scientists at the University of California, San Diego (UCSD), helps elucidate some of the molecular mechanisms behind why brain cells deteriorate with age.

1 week ago | genengnews.com | Uduak Grace Thomas

Home Topics Drug Discovery Neurodegeneration Slowed by Sleep Aid That Reduces Tau Buildup in Mice Credit: Alfred Pasieka/Science Photo Library/Getty Images Credit: Alfred Pasieka/Science Photo Library/Getty Images Data from a new study in mice shows that a common sleep aid protects the brain from damage seen in neurodegenerative disorders, in addition to improving rest.