Cristeena Josphien

Oct 6, 2024 | biorxiv.org | Anirban Roy |Aniket Joshi |Anh Tuan Vuong |Cristeena Josphien

AbstractCachexia is an involuntary loss of body weight mostly due to skeletal muscle wasting. The proinflammatory cytokine TWEAK and its receptor Fn14 constitute a major signaling system that regulates skeletal muscle mass in diverse conditions. However, the role of TWEAK/Fn14 system in the regulation of skeletal muscle mass during cancer-induced cachexia remains poorly understood.