Cristina Lopez-Rodriguez

Sep 14, 2023 | nature.com | Massimo Andreatta |Cristina Lopez-Rodriguez |George Coukos |Melita B. Irving |Santiago J Carmona |Werner Held | +2 more

AbstractPersistent exposure to antigen during chronic infection or cancer renders T cells dysfunctional. The molecular mechanisms regulating this state of exhaustion are thought to be common in infection and cancer, despite obvious differences in their microenvironments.