Dajun Zhang

Sep 7, 2024 | biorxiv.org | Haixin Sarah Bi |Fei Wang |Lin Evlin |Dajun Zhang

AbstractPasteurella multocida toxin (PMT) is an exotoxin produced by several members of the zoonotic respiratory pathogen P. multocida. The role of PMT in disrupting the mammalian respiratory barrier remains to be elucidated. In this study, we discovered that inoculation of recombinantly expressed PMT increased the permeability of the respiratory epithelial barrier in mouse and respiratory cell models.

May 9, 2023 | pubs.rsc.org | Xing Lin |Dajun Zhang |Jing Li |Lei Zhang

Catalyst- and solvent-free regioselective ring opening of aziridines with amines: application to gram-scale synthesis of α, β-diamino propionic derivative, aspergillomarasmine A Xing Lin,   Dajun Zhang,   Jing Li  and  Lei Zhang   Abstract A green and efficient approach to synthesizing α, β-diamino propionic derivatives was developed through ring opening of α-C-alkyloxycarbonyl aziridines.