Daniel Roe

2 weeks ago | dx.doi.org | Lexin Chen |Micah Smith |Daniel Roe |Ramón Alain Miranda-Quintana

2 weeks ago | pubs.acs.org | Lexin Chen |Micah Smith |Daniel Roe |Ramón Alain Miranda-Quintana

Oct 29, 2024 | nist.gov | Olivia Love |Rodrigo Galindo-Murillo |Daniel Roe |Pablo D. Dans

Olivia Love, Rodrigo Galindo-Murillo, Daniel Roe, Pablo D. Dans, Thomas E. Cheatham III, Modified nucleic acids have surged as a popular therapeutic route, emphasizing the importance of nucleic acid research in drug discovery and development. Beyond well-known RNA vaccines, antisense oligonucleotides and aptamers can incorporate various modified nucleic acids to target specific biomolecules for various therapeutic activities.

Oct 29, 2024 | dx.doi.org | Olivia Love |Rodrigo Galindo-Murillo |Daniel Roe |Pablo D. Dans

IntroductionClick to copy section linkSection link copied!As the blueprint for all biological functions, nucleic acids (NA) are at the forefront of various research fields, especially the biochemical and pharmaceutical disciplines. Beyond the canonical nucleotides–adenine, cytosine, guanine, and thymine/uracil–there are a significant number of NA modifications, both natural and unnatural or synthetic.

Aug 16, 2024 | dev.to | Daniel Roe

If you want to use AI to help you contribute to one of the projects I maintain, I would be delighted. But I have rules. Here's my take: Tech gives superpowers to people. For good or ill, technology is a force multiplier. It enables. Unlocks. And I'm thrilled that so-called 'AI' and the careful use of LLMs might empower people to contribute to open source and help them achieve amazing things. In fact, I'm experimenting with AI in some of the projects I maintain, using maige, dosu and more.