Articles

  • Jan 14, 2025 | the-scientist.com | Danielle M. Gerhard

    Endometriosis affects nearly one in 10 women of reproductive age and is marked by the growth of uterine-like tissue outside of the organ, causing severe pelvic pain and infertility. With no cure for endometriosis, treatments are limited to pain relivers, hormonal contraceptives and agonists, and surgery. However, these can lead to menopausal symptoms and bone density loss, and surgery has a high relapse rate.

  • Jan 13, 2025 | the-scientist.com | Shelby Bradford |Danielle M. Gerhard |Laura Tran |Hannah Thomasy

    Article A Sweeter Living Space Promoted Bacterial Survival in Flies Patients with increased blood sugar concentration often experience increased disease severity following infection.1 In 2015, Brian Lazzaro, a geneticist studying host-pathogen interactions at Cornell University, and his group demonstrated that lifetime high-sugar diets made flies more susceptible to Providencia rettgeri .2 “I was interested in looking into what were some of the physiological mechanisms that led to diet having...

  • Dec 2, 2024 | the-scientist.com | Laura Tran |Shelby Bradford |Danielle M. Gerhard |Hannah Thomasy

    ArticleProtein Makeover with Custom Amino AcidsProteins are built by mixing and matching amino acids, but researchers want to create new functions by adding noncanonical amino acids (ncAAs). However, this process often requires complex whole genome editing. This inspired Ahmed Badran, a chemical and synthetic biologist at the Scripps Research Institute, to develop an easier method for adding ncAAs to proteins.

  • Nov 15, 2024 | the-scientist.com | Danielle M. Gerhard

    A decade ago, Aki Sinkkonen, an ecologist at the Natural Resources Institute Finland, went on a wilderness hike with an immunologist colleague.

  • Nov 15, 2024 | the-scientist.com | Laura Tran |Shelby Bradford |Danielle M. Gerhard |Stella Zawistowski

    Epic Fail| ArticleThe Great Flask-tastropheAs a master’s student at Colorado State University in the late 1980s, I worked on developing a purification protocol for an antiviral enzyme, 2-5A synthetase.1 This enzyme, induced by interferons, targeted viral RNA with an RNase, and was enriched in immature red blood cells called reticulocytes. Collecting large amounts of rabbit reticulocytes took weeks of preparation.

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