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1 month ago | 
the-scientist.com | Shelby Bradford
Overlaying reality with simulations advances research and interventions in human behavior and neurodegenerative disorders.
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Jan 15, 2025 | 
the-scientist.com | Shelby Bradford
Cellular communication is vital for passing information to neighboring cells. One key messenger in this process is an exosome, a nanosized particle that buds off from a progenitor cell, carrying molecular cargo. Because these small, cellular vehicles carry contents from their parent cells, exosomes can serve as snapshots for a given population of cells, including tumors.
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Jan 14, 2025 | 
the-scientist.com | Shelby Bradford
Patients with increased blood sugar concentration often experience increased disease severity following infection.1 In 2015, Brian Lazzaro, a geneticist studying host-pathogen interactions at Cornell University, and his group demonstrated that lifetime high-sugar diets made flies more susceptible to Providencia rettgeri .2 “I was interested in looking into what were some of the physiological mechanisms that led to diet having an effect on infection outcome from that work,” said Andrea Darby,...
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Jan 14, 2025 | 
the-scientist.com | Shelby Bradford
To overcome antibiotic resistance, researchers are exploring strategies to improve the function of existing drugs through targeted delivery. A team at the Sichuan Agricultural University leveraged the specificity of bacteriophages to guide antibiotics to specific bacteria.1
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Jan 13, 2025 | 
the-scientist.com | Shelby Bradford |Danielle M. Gerhard |Laura Tran |Hannah Thomasy
Article A Sweeter Living Space Promoted Bacterial Survival in Flies Patients with increased blood sugar concentration often experience increased disease severity following infection.1 In 2015, Brian Lazzaro, a geneticist studying host-pathogen interactions at Cornell University, and his group demonstrated that lifetime high-sugar diets made flies more susceptible to Providencia rettgeri .2 “I was interested in looking into what were some of the physiological mechanisms that led to diet having...
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Jan 8, 2025 | 
the-scientist.com | Shelby Bradford
Vaccination has been an undeniable success in reducing the severity and lethality of pathogenic infections. However, the disconnect between the site of vaccination and the route of pathogen exposure, such as the airways in the case of respiratory pathogens, means that many vaccines still struggle to effectively protect against the initial infection.
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Dec 13, 2024 | 
the-scientist.com | Shelby Bradford
In 1947, Jacques Monod, a biochemist at the Pasteur Institute, observed that Escherichia coli metabolized lactose only if glucose, the bacteria’s preferred sugar source, was absent.1 He began studying the system by investigating the lactose-digesting enzyme, β-galactosidase.2 Although he identified various substrates of the enzyme, the regulatory mechanism that controlled the metabolic switch remained elusive.3 When biologist François Jacob joined the institute in 1950, his research on how...
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Dec 9, 2024 | 
the-scientist.com | Shelby Bradford
When Carlo Quintanilla started graduate school at the University of Texas Southwestern Medical Center, he dove headfirst into his research, exploring the world of specialized proteins and how they regulate lipid metabolism. However, he soon found himself at a crossroads frequented by many: What did he want to do after graduate school? He knew that science policy was a possible career choice but not necessarily what it involved. “I just had a general idea of what it could mean,” Quintanilla said.
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Dec 6, 2024 | 
the-scientist.com | Shelby Bradford
Homologous defense proteins in archaea and eukaryotes point to these early prokaryotes' role in the immune system of modern complex organisms. Current hypotheses suggest that all life on Earth evolved from a common ancestor that diversified into the variety of organisms seen today.
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Dec 2, 2024 | 
the-scientist.com | Shelby Bradford
Beata Mierzwa, a postdoctoral researcher at the University of California, San Diego combines science and art through her brand, Beata Science Art. As an IF/THEN ambassador for the American Association for the Advancement of Science, she inspires girls and other underrepresented groups to explore careers in STEM.
