Danny Wan

Nov 15, 2024 | biorxiv.org | Danny Wan |Matthew Pan |Guangming Zhong |Huizhou Fan

AbstractThe virulence plasmid of the obligate intracellular bacterium Chlamydia encodes eight proteins. Among these, Pgp3 is crucial for pathogenicity, and Pgp4 functions as a transcriptional regulator of both plasmid and chromosomal genes. The remaining proteins, Pgp1, Pgp5, Pgp6, Pgp7, and Pgp8, are predicted to play various roles in plasmid replication or maintenance based on their amino acid sequences. However, the function of Pgp2 remains unknown, even though it is required for transformation.

May 21, 2024 | biorxiv.org | Danny Wan |Andrew Cheng |Yuxuan Wang |Guangming Zhong

AbstractMotivation: RNA sequencing (RNA-Seq) offers profound insights into the complex transcriptomes of diverse biological systems. However, standard differential expression analysis pipelines based on DESeq2 and edgeR encounter challenges when applied to the immediate early transcriptomes of Chlamydia spp., obligate intracellular bacteria.

Apr 11, 2024 | sfchronicle.com | Danny Wan

Say someone wanted to come to the Bay Area to spend a weekend in Wine Country, meet with colleagues at one of the three national laboratories in the East Bay, or even just visit family or friends. Many of these visitors, who may be unfamiliar with our local geography, would automatically assume the closest airport is San Francisco International Airport. But they’d be wrong. In all these instances and many others, the Metropolitan Oakland International Airport is closer.

Jul 12, 2023 | link.aps.org | Danny Wan