Darshan Aatmaram Jadhav

Mar 6, 2024 | mdpi.com | Ronghao Zhang |Darshan Aatmaram Jadhav |Benjamin Kramer |Benjamin Krämer |Najeong Kim

All articles published by MDPI are made immediately available worldwide under an open access license. No specialpermission is required to reuse all or part of the article published by MDPI, including figures and tables. Forarticles published under an open access Creative Common CC BY license, any part of the article may be reused withoutpermission provided that the original article is clearly cited. For more information, please refer tohttps://www.mdpi.com/openaccess.

Dec 22, 2023 | biorxiv.org | Ronghao Zhang |Benjamin Kramer |Benjamin Krämer |Agustin Gonzalez-Vicente |Darshan Aatmaram Jadhav

AbstractSingle-cell RNA sequencing (scRNAseq) is a crucial tool in kidney research. These technologies cluster cells according to transcriptome similarity, irrespective of the anatomical location and ordering within the nephron. Thus, a cluster transcriptome may obscure heterogeneity of the cell population within a nephron segment. Elevated dietary fructose leads to salt-sensitive hypertension, in part by fructose reabsorption in the proximal tubule (PT).