Dinithi Sumanaweera

Dec 21, 2023 | biorxiv.org | Steven Woods |Kenny Roberts |Dinithi Sumanaweera |Petra Balogh

AbstractThe consistent production of in vitro chondrocytes that faithfully recapitulate in vivo development would be of great benefit for musculoskeletal disease modelling and regenerative medicine. Current efforts are often limited by off-target differentiation, resulting in a heterogeneous product. Furthermore, the lack of comparison to human embryonic tissue, precludes detailed evaluation of in vitro cells.