Dmitry S. Karlov

Mar 23, 2023 | cell.com | Sarah Long |APC Microbiome Ireland |Ximin Zeng |Dmitry S. Karlov

Regression models constructionThe binding energy decomposition for the set of mutant enzyme/substrate pairs led to a matrix with dimensions N x M (the number of observations where each observation denotes the relative ability to hydrolyze a specific bile acid by a chosen mutant enzyme vs a number of amino acids in a tetramer), where each cell i, j content represents the interaction energy between j amino acid of i mutant and the substrate.