Edoardo Fatti

Apr 25, 2023 | science.org | Dhanendra Tomar |Edoardo Fatti |Larisa I. Labzin |Keng Yih Chew

Antiviral actions only when infected through ACE2Macrophages are critical first responders to infection but are also implicated in driving severe inflammation, particularly in patients with SARS-CoV-2. Because relatively few lung-resident macrophages have the putative SARS-CoV-2 receptor ACE2, Labzin et al. explored its role in the response of these cells to viral infection.

Apr 25, 2023 | science.org | Thierry Gauthier |Yubo Cao |Wei Wong |Edoardo Fatti

Published In Science SignalingVolume 16 | Issue 782April 2023Article versionsSubmission historyReceived: 8 March 2022Accepted: 5 April 2023PermissionsRequest permissions for this article. AcknowledgmentsWe thank L. Rohland and M. Mayer (ZMBH Heidelberg) for the help with stopped flow measurements. We thank C. Reinhard, N. Dirdjaja, and A. Wendlandt for expert technical assistance and J. Oakhill (University of Melbourne) for advice and supply with the P81 paper. We thank I.