Wei Wong
Deputy Editor at Science Magazine
Uncovering mechanisms in biology, gaining insights into physiology and disease.
Articles
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2 weeks ago |
radii.co | Wei Wong
In every city, there is a stylist who becomes the go-to for models and influencers in need of a transformative hairstyle. In Singapore, that stylist is none other than Junz Loke. Known for his rebellious spirit, verve, and meticulous skill, Loke has become the trusted hand behind the looks of local celebrities and global trendsetters alike.
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1 month ago |
medrxiv.org | Wei Wong |Tan Van Nguyen |Vien Nguyen |Tu Ngoc Nguyen |Tú Nguyên
The authors have declared no competing interest. This study did not receive any fundingI confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained.
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1 month ago |
science.org | Wei Wong
Skip to main content Main content starts here AbstractROS generated by sleep-promoting neurons tracks the need for sleep and initiates sleep. SIGN UP FOR THE AWARD-WINNING SCIENCEADVISER NEWSLETTER The latest news, commentary, and research, free to your inbox daily Sleep is thought to prevent oxidative damage to neurons. Tian et al.
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1 month ago |
science.org | Mingming Zhang |Sagar Shah |Wei Wong |Chunxiao Ren
Editor’s summaryThe transcriptional coactivator YAP promotes development and wound healing and is implicated in various diseases. Shah et al. found that YAP promoted cell motility by inducing a switch in the activity of Rho family GTPases. YAP-TEAD4 complexes mediated the induction of TRIO, a guanine nucleotide exchange factor that activated Rac1 and consequently inhibited RhoA, resulting in increased cell migration and invasion.
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1 month ago |
prod--journal.elifesciences.org | Wei Wong |Yi Zhu |Hai Wang |Jia Qian
eLife assessment This study presents valuable findings on the mechanisms underlying a rare brain disease using an organoid system. In this revised version, there are remaining reviewers' comments that are not yet addressed and as such, while the data presented are solid, the evidence supporting some of the claims is deemed incomplete. The work will be of interest to neuroscientists and clinicians aiming to understand and combat similar neurodegenerative disorders.
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In the new issue, researchers tie metastasis and the spread of #PancreaticCancer cells to mutations that enhance the activity of the enzyme TRIM21, a finding that could support research into new targeted therapies. @SCUCN https://t.co/519teDhbTd https://t.co/Wk2L3j9PZ1
A molecular pathway centered on a receptor named Npr2 sensitizes neurons to pain sensations in mice and could offer a potential therapeutic target in both acute and chronic pain, according to a new preclinical study. @goetheuni https://t.co/dP8LgVSn4z https://t.co/LAuyOTXbdn
Through experiments in vitro and in mice, researchers have discovered how the protein SMAD2 promotes the development of proinflammatory T cells, which may have implications for the treatment of some autoimmune diseases. @CornellChem https://t.co/sev8upEZiw https://t.co/NP9EfsDnWr