
Wei Wong
Deputy Editor at Science Magazine
Uncovering mechanisms in biology, gaining insights into physiology and disease.
Articles
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1 week ago |
science.org | Wei Wong
Skip to main content Main content starts here AbstractROS generated by sleep-promoting neurons tracks the need for sleep and initiates sleep. SIGN UP FOR THE AWARD-WINNING SCIENCEADVISER NEWSLETTER The latest news, commentary, and research, free to your inbox daily Sleep is thought to prevent oxidative damage to neurons. Tian et al.
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1 week ago |
science.org | Mingming Zhang |Sagar Shah |Wei Wong |Chunxiao Ren
Editor’s summaryThe transcriptional coactivator YAP promotes development and wound healing and is implicated in various diseases. Shah et al. found that YAP promoted cell motility by inducing a switch in the activity of Rho family GTPases. YAP-TEAD4 complexes mediated the induction of TRIO, a guanine nucleotide exchange factor that activated Rac1 and consequently inhibited RhoA, resulting in increased cell migration and invasion.
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2 weeks ago |
prod--journal.elifesciences.org | Wei Wong |Yi Zhu |Hai Wang |Jia Qian
eLife assessment This study presents valuable findings on the mechanisms underlying a rare brain disease using an organoid system. In this revised version, there are remaining reviewers' comments that are not yet addressed and as such, while the data presented are solid, the evidence supporting some of the claims is deemed incomplete. The work will be of interest to neuroscientists and clinicians aiming to understand and combat similar neurodegenerative disorders.
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1 month ago |
science.org | Bianca Lopez |Wei Wong |Phil Szuromi |Ian S. Osborne |Michael Funk |Jelena Stajic | +8 more
Bird Decline Patterns of lossBianca LopezWetlands, such as the bald cypress forest at Caddo Lake, Texas, pictured here, are experiencing serious declines in bird populations. PHOTO: WANDERLUSTER/ISTOCK PHOTOWe know that birds are declining globally, but more fine-scale information on population trends is needed to guide conservation efforts. Johnston et al.
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1 month ago |
science.org | Lien Nguyen |Wei Wong
Editors' ChoiceMETABOLISMWei Wong https://orcid.org/0009-0008-7154-4108 [email protected] Info & AffiliationsAbstractCovalent protein modification with endogenously produced cyanide supports mammalian cell proliferation. SIGN UP FOR THE AWARD-WINNING SCIENCEADVISER NEWSLETTER The latest news, commentary, and research, free to your inbox daily Many biologically necessary substances become toxic at excessive amounts. Zuhra et al.
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Scientists construct a massive atlas of bacterial kinases to inform antibiotic development, a new Review explores the latest findings about an enzyme essential to the nervous and immune systems, and more in this week’s issue of #ScienceSignaling. https://t.co/iWHPEFaGkG https://t.co/q5ZRbXdoCo

A new study in mice reveals how cells called #pericytes fine-tune blood pressure in the brain’s capillaries through the channel protein TRPC3, hinting it might offer a target in disorders involving disruptions in cerebral blood flow. @CUSOMAnesthesia https://t.co/RpZ1pnBr1g https://t.co/45VyZ14CAf

Researchers build an intracellular profile of dormancy in aggressive #BreastCancer cells and show that OVOL transcription factors support dormancy and survival by stimulating selective #autophagy and suppressing antioxidant signaling. @WeizmannScience https://t.co/3s0BTIV7VQ https://t.co/NYJ2hczz4m