Eileen White

Featured in: Favicon

nature.com Favicon

aacrjournals.org Favicon

cancerres.aacrjournals.org

Articles

Glucose-6-phosphate dehydrogenase maintains redox homeostasis and biosynthesis in LKB1-deficient KRAS-driven lung cancer - Nature Communications

Jul 11, 2024 | nature.com | Samuel Wang |Eduardo Lopes |Jonathan M. Ghergurovich |Xiaoyang Su |Joshua D. Rabinowitz |Eileen White

AbstractCancer cells depend on nicotinamide adenine dinucleotide phosphate (NADPH) to combat oxidative stress and support reductive biosynthesis. One major NADPH production route is the oxidative pentose phosphate pathway (committed step: glucose-6-phosphate dehydrogenase, G6PD). Alternatives exist and can compensate in some tumors.

Contact details

Emails

[email protected]

Socials & Sites

Try JournoFinder For Free

Search and contact over 1M+ journalist profiles, browse 100M+ articles, and unlock powerful PR tools.

Start Your 7-Day Free Trial →