Elisabeth Schreivogel

Apr 20, 2024 | biorxiv.org | Mani Erfanian Abdoust |Monja Isabel Froböse |Alfons Schnitzler |Elisabeth Schreivogel

AbstractIn everyday life, we encounter situations that require tradeoffs between potential rewards and associated costs, such as time and (physical) effort. The literature indicates a prominent role for dopamine in discounting of both delay and effort, with mixed findings for delay discounting in humans. Moreover, the reciprocal antagonistic interaction between dopaminergic and cholinergic transmission in the striatum suggests a potential opponent role of acetylcholine in these processes.

Nov 21, 2023 | biorxiv.org | Mani Erfanian Abdoust |Monja Isabel Froböse |Alfons Schnitzler |Elisabeth Schreivogel

AbstractIn everyday life, we encounter situations that require tradeoffs between potential rewards and associated costs, such as time and (physical) effort. The literature indicates a prominent role for dopamine in discounting of both delay and effort, with mixed findings for delay discounting in humans. Moreover, the reciprocal antagonistic interaction between dopaminergic and cholinergic transmission in the striatum suggests a potential opponent role of acetylcholine in these processes.