Elizabeth E. Powell

Mar 10, 2025 | onlinelibrary.wiley.com | Julia James |Madeline P Fuller |Madison Hunt |Elizabeth E. Powell

Background Prior studies of anticoagulation bridging during periods of low International Normalized Ratio (INR) in outpatients with a durable, continuous flow left ventricular assist device (CF-LVAD) have shown a variable impact on thrombotic and bleeding events. These studies include predominantly older devices such as the HeartMate 2 (HM2) and HeartWare HVAD, which are known to experience more overall thrombotic events than the HeartMate 3 (HM3) device.

Sep 4, 2023 | analyticalsciencejournals.onlinelibrary.wiley.com | Elizabeth E. Powell |Ben Dickie |Yolanda Ohene |Human Neuroscience

1 INTRODUCTION The blood–brain barrier (BBB) plays a vital role in regulating and maintaining healthy brain function. Passive diffusion of solutes and potential neurotoxins from the blood into the brain is tightly restricted, with the transport of necessary metabolites controlled by specialized proteins.