Emma Colliver

Jan 9, 2025 | nature.com | Dhruva Biswas |Yun-Hsin Liu |Javier Herrero |Yin Chao Wu |David Moore |Takahiro Karasaki | +18 more

AbstractHuman tumors are diverse in their natural history and response to treatment, which in part results from genetic and transcriptomic heterogeneity. In clinical practice, single-site needle biopsies are used to sample this diversity, but cancer biomarkers may be confounded by spatiogenomic heterogeneity within individual tumors.

Jul 4, 2024 | nature.com | Alexander Frankell |Michelle Dietzen |Maise Al Bakir |Takahiro Karasaki |Sophia Ward |Emma Colliver | +25 more

Correction to: Nature https://doi.org/10.1038/s41586-023-05783-5 Published online 12 April 2023In the version of the article initially published, the symbols for death (x) and censored (>) were swapped in the graphs in Fig. 1. The figure has now been corrected in the HTML and PDF versions of the article.

Nov 28, 2023 | nature.com | Kristiana Grigoriadis |Ariana Huebner |Abigail Bunkum |Emma Colliver |Alexander Frankell |Kerstin Thol | +3 more

AbstractIntratumor heterogeneity provides the fuel for the evolution and selection of subclonal tumor cell populations. However, accurate inference of tumor subclonal architecture and reconstruction of tumor evolutionary histories from bulk DNA sequencing data remains challenging.