Emma Dempster

Dec 6, 2024 | theconversation.com | Marta Di Forti |Emma Dempster

A maconha é uma das drogas mais comumente usadas no mundo. No entanto, ainda há muito que não sabemos sobre ela e seus efeitos no cérebro, inclusive o motivo pelo qual desencadeia psicose em algumas pessoas que a consomem. Mas, nosso recente estudo acaba de nos aproximar da compreensão do impacto biológico da cannabis de alta potência. Publicado na revista Molecular Psychiatry, nossa pesquisa demonstra que a cannabis de alta potência deixa uma marca distinta no DNA.

Nov 25, 2024 | psypost.org | Marta Di Forti |Emma Dempster

Cannabis is one of the most commonly used drugs in the world. Yet there’s still much we don’t know about it and what effects it has on the brain – including why cannabis triggers psychosis in some people who use the drug. But our recent study has just brought us closer to understanding the biological impact of high-potency cannabis use. Published in the journal Molecular Psychiatry, our study demonstrates that high-potency cannabis leaves a distinct mark on DNA.

Oct 17, 2024 | sciencealert.com | Emma Dempster |Marta Di Forti

Cannabis is one of the most commonly used drugs in the world. Yet there's still much we don't know about it and what effects it has on the brain – including why cannabis triggers psychosis in some people who use the drug. But our recent study has just brought us closer to understanding the biological impact of high-potency cannabis use. Published in the journal Molecular Psychiatry, our study demonstrates that high-potency cannabis leaves a distinct mark on DNA.

Oct 15, 2024 | nature.com | Emma Dempster |Eilis Hannon |Diego Quattrone |Edoardo Spinazzola |Zhikun Li |Charlotte Gayer-Anderson | +17 more

AbstractThe rising prevalence and legalisation of cannabis worldwide have underscored the need for a comprehensive understanding of its biological impact, particularly on mental health. Epigenetic mechanisms, specifically DNA methylation, have gained increasing recognition as vital factors in the interplay between risk factors and mental health.

Apr 16, 2023 | nature.com | Luis Alameda |Zhonghua Liu |Celso Arango |Miguel Bernardo |Julio Bobes |Peter Jones | +14 more

AbtractStudies conducted in psychotic disorders have shown that DNA-methylation (DNAm) is sensitive to the impact of Childhood Adversity (CA). However, whether it mediates the association between CA and psychosis is yet to be explored. Epigenome wide association studies (EWAS) using the Illumina Infinium-Methylation EPIC array in peripheral blood tissue from 366 First-episode of psychosis and 517 healthy controls was performed.