Edoardo Spinazzola

Jan 17, 2025 | kcl.ac.uk | Edoardo Spinazzola |Edward Chesney |Charlotte Gayer-Anderson

New research reports that cannabis users' risk of developing psychotic disorders appears to decrease with time once they stop using the drug. New research from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King’s College London has reported that cannabis users' risk of developing psychotic disorders appears to decrease with time once they stop using the drug.

Oct 15, 2024 | nature.com | Emma Dempster |Eilis Hannon |Diego Quattrone |Edoardo Spinazzola |Zhikun Li |Charlotte Gayer-Anderson | +17 more

AbstractThe rising prevalence and legalisation of cannabis worldwide have underscored the need for a comprehensive understanding of its biological impact, particularly on mental health. Epigenetic mechanisms, specifically DNA methylation, have gained increasing recognition as vital factors in the interplay between risk factors and mental health.

Aug 1, 2024 | nature.com | Zhikun Li |Diptendu Mukherjee |Bea Duric |Diego Quattrone |Robin Murray |Edoardo Spinazzola

AbstractThe link between cannabis use and schizophrenia is well-established in epidemiological studies, especially among adolescents with early-onset use. However, this association in rodent models is less clear. This meta-analysis examined the effects of adolescent cannabinoid exposure on distinct schizophrenia-like behaviours in rodents and how experimental variations influence outcomes.