Ester Gonzalez-Sanchez

Jun 14, 2024 | pathsocjournals.onlinelibrary.wiley.com | Ester Gonzalez-Sanchez |Digestive Diseases |ISCIII Madrid Spain |Javier Vaquero

Introduction Fibrosis is a highly conserved and coordinated, initially protective, response to tissue injury. The interaction among multiple pathways determines whether fibrosis is self-limiting and homeostatic or whether it is uncontrolled and excessive [1]. When a chronic injury takes place in the liver, mobilization of lymphocytes and other inflammatory cells occurs, thus setting the stage for persistence of an inflammatory response.

Nov 5, 2023 | biorxiv.org | Ester Gonzalez-Sanchez |Javier Vaquero |Jan Grzelak |Daniel Caballero-Diaz

AbstractBackground & Aims: Liver fibrosis is the consequence of chronic liver injury in the presence of an inflammatory component. Although the main executors of this activation are known, the mechanisms that lead to the inflammatory process that mediates the production of profibrotic factors are not well characterized.