ISCIII Madrid Spain

Jun 14, 2024 | pathsocjournals.onlinelibrary.wiley.com | Ester Gonzalez-Sanchez |Digestive Diseases |ISCIII Madrid Spain |Javier Vaquero

Introduction Fibrosis is a highly conserved and coordinated, initially protective, response to tissue injury. The interaction among multiple pathways determines whether fibrosis is self-limiting and homeostatic or whether it is uncontrolled and excessive [1]. When a chronic injury takes place in the liver, mobilization of lymphocytes and other inflammatory cells occurs, thus setting the stage for persistence of an inflammatory response.