Eva F. Hayball

Sep 13, 2024 | chemistry-europe.onlinelibrary.wiley.com | Tuhin Das |Eva F. Hayball |Alix C. Harlington |Biomedical Science

Introduction Cytochrome P450 enzymes (CYPs) are a group of heme-thiolate enzymes that catalyse the regio- and stereo-selective oxidation of carbon-hydrogen (C−H) bonds in organic compounds.1 The enzymes participate in a wide range of chemical reactions including; decarboxylation, epoxidation, desaturation, dealkylation, and sulfoxidation.2 They are therefore of significant interest as biocatalysts to simplify synthetic routes involving selective late-stage functionalisation of complex...