Fédération Hospitalo-Universitaire

Apr 22, 2024 | link.springer.com | Université Paris |Fédération Hospitalo-Universitaire |APC Microbiome Ireland

AbstractThe etiology of inflammatory bowel disease (IBD) is unclear but involves both genetics and environmental factors, including the gut microbiota. Indeed, exacerbated activation of the gastrointestinal immune system toward the gut microbiota occurs in genetically susceptible hosts and under the influence of the environment. For instance, a majority of IBD susceptibility loci lie within genes involved in immune responses, such as caspase recruitment domain member 9 (Card9).