Felix Mahfoud

1 month ago | nature.com | Mathias Hohl |Mert Tokcan |Jan M. Federspiel |Peter Boor |Markus Meyer |Felix Mahfoud

AbstractThe diuretic drug hydrochlorothiazide (HCT) is associated with an increased risk of non-melanoma skin cancer upon UV exposure. The underlying cellular and molecular mechanisms behind this association remain elusive. Herein, a human skin model to assess the photocarcinogenic effects of HCT is established. Skin biopsies collected from human body donors are treated with HCT and irradiated with 300 mJ/cm2 low dose UVA or UVB or with 5 J/cm2 high dose UVA.

Nov 27, 2024 | radcliffecardiology.com | Ashley Park |Marc P. Bonaca |Sahil A. Parikh |Felix Mahfoud

AHA Conference 2024 - New insights from the CLEAR OUTCOMES trial investigating bempedoic acid (Esperion Therapeutics Inc.) in statin-intolerant patients with peripheral arterial disease (PAD). Dr Marc Bonaca (University of Colorado School of Medicine, Colorado, US) joins us onsite at AHA Conference to discuss new insights from CLEAR OUTCOMES (NCT02993406).

Sep 18, 2024 | onlinelibrary.wiley.com | Gabriela M. Kuster |Birgit Assmus |Felix Mahfoud

Invited Editorial Myeloperoxidase: Reviving an old ally for immunomodulation in heart failure? Inhibition of myeloperoxidase to treat left ventricular dysfunction in non-ischaemic cardiomyopathy Simon Geissen, Simon Braumann, Joana Adler, Felix Sebastian Nettersheim, Dennis Mehrkens, Alexander Hof, Henning Guthoff, Philipp von Stein, Sven Witkowski, Norbert Gerdes, Frederik Tellkamp, Marcus Krüger, Lea Isermann, Aleksandra Trifunovic, Alexander C.