Feng Cai

Aug 5, 2024 | dovepress.com | Feng Cai |Li-Li Xu |Xin Tang |Lin-Lin Wang

Back to Journals » Diabetes, Metabolic Syndrome and Obesity » Volume 17 Authors Cai F, Xu LL, Tang X, Wang LL Received 5 August 2024 Accepted for publication 28 October 2024 Published 5 November 2024 Volume 2024:17 Pages 4167—4176 DOI https://doi.org/10.2147/DMSO.S483457 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Prof.

Jul 2, 2024 | cell.com | Zheng Wu |Divya Bezwada |Feng Cai |Robert Harris

Highlights•ETC inhibition rewires purine metabolism•Cytosolic NAD(H) imbalance induces purine accumulation in ETC-deficient cells•HPRT1-mediated purine salvage supports NSCLC growth during ETC inhibition•Purine uptake is required to supply salvage upon ETC inhibitionSummaryMitochondria house many metabolic pathways required for homeostasis and growth.

Jun 13, 2024 | cell.com | Zheng Wu |Divya Bezwada |Feng Cai |Robert Harris

Highlights•ETC inhibition rewires purine metabolism•Cytosolic NAD(H) imbalance induces purine accumulation in ETC-deficient cells•HPRT1-mediated purine salvage supports NSCLC growth during ETC inhibition•Purine uptake is required to supply salvage upon ETC inhibitionSummaryMitochondria house many metabolic pathways required for homeostasis and growth.