Robert Harris

Dec 20, 2024 | nature.com | Robert Harris

Correction to: Scientific Reports https://doi.org/10.1038/s41598-024-74359-8, published online 22 October 2024In the original article, the typesetter omitted the below Reference, which is listed below as Reference 1. 1. Saito, T. et al. Single App knock-in mouse models of Alzheimer’s disease. Nat. Neurosci. 17, 661–663 (2014).

Jun 13, 2024 | cell.com | Zheng Wu |Divya Bezwada |Feng Cai |Robert Harris

Highlights•ETC inhibition rewires purine metabolism•Cytosolic NAD(H) imbalance induces purine accumulation in ETC-deficient cells•HPRT1-mediated purine salvage supports NSCLC growth during ETC inhibition•Purine uptake is required to supply salvage upon ETC inhibitionSummaryMitochondria house many metabolic pathways required for homeostasis and growth.

Dec 1, 2023 | biorxiv.org | Kateryna D. Makova |Brandon Pickett |Robert Harris |Gabrielle Hartley

IntroductionTherian X and Y chromosomes are thought to have originated from a pair of autosomes approximately 170 million years ago (MYA)1. The X chromosome, typically present in two copies in females and one copy in males, has mostly retained the gene content and order from the original autosomal pair2.