Florian A. Rosenberger

Apr 29, 2024 | nature.com | Florian A. Rosenberger |Arnaud Mourier |Diana Rubalcava-Gracia |Polyxeni Papadea |Olov Andersson |Raffaella Di Lucrezia | +6 more

AbstractThe oxidative phosphorylation system1 in mammalian mitochondria plays a key role in transducing energy from ingested nutrients2. Mitochondrial metabolism is dynamic and can be reprogrammed to support both catabolic and anabolic reactions, depending on physiological demands or disease states. Rewiring of mitochondrial metabolism is intricately linked to metabolic diseases and promotes tumour growth3,4,5.

May 10, 2023 | nature.com | Dari Shalon |Rebecca Neal Culver |Jessica A. Grembi |Handuo Shi |Florian A. Rosenberger |Sean P Spencer | +5 more

AbstractThe spatiotemporal structure of the human microbiome1,2, proteome3 and metabolome4,5 reflects and determines regional intestinal physiology and may have implications for disease6. Yet, little is known about the distribution of microorganisms, their environment and their biochemical activity in the gut because of reliance on stool samples and limited access to only some regions of the gut using endoscopy in fasting or sedated individuals7.

Mar 10, 2023 | nature.com | Marvin Thielert |Matthias Mann |Florian A. Rosenberger

Author notesThese authors contributed equally: Florian A. Rosenberger, Marvin Thielert. Authors and AffiliationsProteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, GermanyFlorian A. Rosenberger, Marvin Thielert & Matthias MannProteomics Program, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, DenmarkMatthias MannContributionsM.M., M.T. and F.A.R. conceived the original idea.