Franco Blanchini

2 months ago | biorxiv.org | Eiji Nakamura |Franco Blanchini |Giulia Giordano |Alexander Hoffmann

AbstractCells have the capacity to encode and decode information in the temporal features of molecular signals. Many pathways, for example, generate either sustained or pulsatile responses depending on the context, and such diverse temporal behaviors have a profound impact on cell fate. Here we focus on how molec- ular pathways can convert the temporal features of dynamic signals, in particular how they can convert transient signals into persistent downstream events and vice versa.