Frank Britto Bisso

Nov 29, 2024 | biorxiv.org | Frank Britto Bisso |Giulia Giordano |Christian Cuba Samaniego |Carnegie Mellon

AbstractEngineering cell fate is fundamental for optimizing stem cell-based therapies aimed at replacing cells in patients suffering from trauma or disease. By timely administering molecular regulators - such as transcription factors, RNAs, or small molecules - in a process that mimics in vivo embryonic development, stem cell differentiation can be guided toward a specific cell fate.