Gabriele Scorrano

Jan 10, 2024 | nature.com | Evan K. Irving-Pease |Anders Fischer |Karl-Göran Sjögren |Alma Halgren |Ruairidh Macleod |Rasmus Henriksen | +14 more

AbstractThe Holocene (beginning around 12,000 years ago) encompassed some of the most significant changes in human evolution, with far-reaching consequences for the dietary, physical and mental health of present-day populations. Using a dataset of more than 1,600 imputed ancient genomes1, we modelled the selection landscape during the transition from hunting and gathering, to farming and pastoralism across West Eurasia.

Jan 10, 2024 | nature.com | Yaoling Yang |Evan K. Irving-Pease |Kathrine E. Attfield |Gabriele Scorrano |Thorfinn Sand Korneliussen |Martin Sikora | +3 more

AbstractMultiple sclerosis (MS) is a neuro-inflammatory and neurodegenerative disease that is most prevalent in Northern Europe. Although it is known that inherited risk for MS is located within or in close proximity to immune-related genes, it is unknown when, where and how this genetic risk originated1.