Gary G. Koch

Jan 22, 2025 | onlinelibrary.wiley.com | Beth Davison |Gad Cotter |Gary G. Koch

Viewpoint Hierarchical composite outcomes are here to stay, despite the limitations of the win ratio Beth A. Davison,  Corresponding Author Beth A. Davison INSERM UMR-S 942 (MASCOT), Université Paris Cité, Paris, France Momentum Research, Inc, Durham, NC, USA Corresponding author. Momentum Research, Inc, 3100 Tower Blvd, Suite 802, Durham, NC 27707, USA.

May 7, 2024 | onlinelibrary.wiley.com | Andrew Sherwood |James A. Blumenthal |Robert J. Mentz |Gary G. Koch

Introduction Elevated depressive symptoms have been found to be associated with a marked increase in adverse clinical outcomes for heart failure (HF) patients with reduced ejection fraction (HFrEF).1-3 The increased risk of adverse clinical outcomes associated with elevated depressive symptoms in HFrEF patients is substantial, even in the absence of levels that denote clinical depression.3-6 There is also evidence that depressive symptoms that increase or worsen over time may signal HF...