Ge Zhang

Dec 30, 2024 | mdpi.com | Ge Zhang

1. IntroductionTraditional chemotherapy frequently causes severe adverse effects due to its lack of specificity [1]. Targeted therapy has emerged as a promising strategy to improve treatment efficacy while reducing side effects [2,3]. Paclitaxel (PTX) prodrugs designed for specific tumors can be classified into small-molecule–PTX conjugates (SMDCs), antibody–PTX conjugates (ADCs), and aptamer–PTX conjugates (ApDCs).

Nov 28, 2024 | mdpi.com | Shuai Li |Junliang Gao |Pu Guo |Ge Zhang

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Aug 23, 2024 | bmcgenomics.biomedcentral.com | Huan Xu |Ge Zhang |JING CHEN

DiscussionIn our study, we introduced a novel approach for cell type deconvolution using DNA methylation data by performing the analysis in PCA space. This method stands in contrast to existing approaches that operate at the probe level, such as IDOL-Ext, CIBERSORT, EpiDISH and EMeth. The key distinction of our approach lies in the data representation used for deconvolution, which is independent of the specific probe selection and cell type proportion estimation techniques employed.

Nov 8, 2023 | arxiv.org | Ge Zhang |Jie Fu

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Oct 23, 2023 | journals.plos.org | Anu Pasanen |Minna K. Karjalainen |Ge Zhang |Heli Tiensuu

Loading metrics Open Access Peer-reviewedResearch Article ? This is an uncorrected proof. Citation: Pasanen A, Karjalainen MK, FinnGen, Zhang G, Tiensuu H, Haapalainen AM, et al. (2023) Meta-analysis of genome-wide association studies of gestational duration and spontaneous preterm birth identifies new maternal risk loci. PLoS Genet 19(10): e1010982. https://doi.org/10.1371/journal.pgen.1010982Editor: Vincent J.