Giacomina Brunetti

Nov 2, 2023 | frontiersin.org | Sun Yat-sen |Giacomina Brunetti |Sulev Kõks

1 IntroductionOsteogenesis imperfecta (OI) is a rare, hereditary, clinically heterogeneous, primary bone dysplasia characterized by increased bone fragility, low bone mass, and susceptibility to bone fractures. Other clinical manifestations include short stature, blue scleral hue, dentinogenesis imperfecta, progressive post-pubertal hearing loss, ligamentous laxity, and so on (1–3).

Mar 28, 2023 | frontiersin.org | Cheeloo College |Xin Huang |Giacomina Brunetti |Xianyong Yin

1 IntroductionBlood pressure lowering through antihypertensive drugs is an established strategy for hypertension management to reduce the risk of developing cardiovascular diseases (1, 2). Hypertension and osteoporosis are often co-existed, especially in the aging population (3). The effects on osteoporosis from antihypertensive drugs can differ due to the diverse mechanisms of action among different classes of these drugs.