Grant Chau
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biorxiv.org
Articles
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1 month ago |
biorxiv.org | Rahul Gupta |Timothy Durham |Grant Chau |Mesbah Uddin
AbstractOne of the strongest signatures of aging is an accumulation of mutant mitochondrial DNA (mtDNA) heteroplasmy. Here we investigate the mechanism underlying this phenomenon by calling mtDNA sequence, abundance, and heteroplasmic variation in human blood using whole genome sequences from ~750,000 individuals.
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