Grant O’Keefe

Apr 26, 2023 | jamanetwork.com | Matthew R. Thau |Ted Liu |Grant O’Keefe

Key PointsQuestion  Are trauma molecular endotypes associated with clinical outcomes and differential response to transfusion resuscitation strategies? Findings  In this secondary analysis of the Pragmatic, Randomized Optimal Platelet and Plasma Ratios (PROPPR) trial including 478 patients, 2 molecular endotypes of trauma patients were identified using a panel of 36 plasma biomarkers collected at the time of hospital arrival.

Feb 7, 2023 | newsroom.uw.edu | Grant O’Keefe

Commonly used systems to identify sepsis fail to detect many cases in patients initially admitted to hospital for severe traumatic injuries, researchers at the University of Washington School of Medicine in Seattle have found. “The failure of these systems to identify these cases likely mean we are underappreciating the importance of sepsis in trauma patients,” said Dr. Grant O’Keefe, a professor of surgery in the Division of Trauma, Burn and Critical Care.