Jonathan Leung

Jan 21, 2025 | biorxiv.org | Andrew Robinson |David Jiang |Abbey Nkansah |Jonathan Leung

AbstractSmall diameter vascular grafts require a complex balance of biomechanical properties to achieve target burst pressure, arterial compliance-matching, and kink resistance to prevent failure. Iterative design of our multilayer vascular was previously used to achieve high compliance while retaining the requisite burst pressure and suture retention strength for clinical use.

Sep 7, 2024 | biorxiv.org | David Jiang |Andrew Robinson |Abbey Nkansah |Jonathan Leung

AbstractThe failure of synthetic small-diameter vascular grafts has been attributed to a mismatch in the compliance between the graft and native artery, driving mechanisms that promote thrombosis and neointimal hyperplasia. Additionally, the buckling of grafts results in large deformations that can lead to device failure. Although design features can be added to lessen the buckling potential, the addition is detrimental to decreasing compliance (e.g., reinforcing coil).

Sep 1, 2024 | nature.com | Jonathan Leung

IntroductionExpert groups differ in their recommendations for early-stage schizophrenia treatment. Some expert groups, including American Psychiatric Association (APA), are non-directive and do not specify preferred agents for patients with first-episode psychosis1,2,3. This approach, while patient-centric, may challenge early practitioners and learners.

Jun 28, 2024 | mondaq.com | Wendy Berman |Robert Hansen |Gurvir Sangha |Jonathan Leung

On May 3, 2024, the Ontario Securities Commission (the "OSC") unveiled its  strategic plan for 2024-2030 (the "Strategic Plan"). With the goal of making Ontario's capital markets inviting, thriving, and secure, the Strategic Plan sets out six strategic goals that will guide the regulator for the next six years.

Jun 25, 2024 | lexology.com | Wendy Berman |Robert Hansen |Gurvir Sangha |Jonathan Leung |RITIKA GUPTA

On May 3, 2024, the Ontario Securities Commission (the “OSC”) unveiled its strategic plan for 2024-2030 (the “Strategic Plan”). With the goal of making Ontario’s capital markets inviting, thriving, and secure, the Strategic Plan sets out six strategic goals that will guide the regulator for the next six years.