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2 months ago | 
link.springer.com | Guangdong Laboratory |South Agricultural |Xianghu Laboratory
AbstractPorcine deltacoronavirus (PDCoV) is a globally distributed swine enteropathogenic virus that emerged in the last decade. A recent report of PDCoV infection in Haitian children also highlights potential public health implications. In this study, two monoclonal antibodies (mAbs), 1C2 and 5H5, were generated and showed high specificity for the PDCoV S protein. Both mAbs displayed high-titer neutralizing capabilities, suggesting their potential for passive immunotherapy.
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Dec 5, 2024 | 
academic.oup.com | Shenzhen Branch |Guangdong Laboratory |Zhuo Liu
Accepted manuscripts are PDF versions of the author’s final manuscript, as accepted for publication by the journal but prior to copyediting or typesetting. They can be cited using the author(s), article title, journal title, year of online publication, and DOI. They will be replaced by the final typeset articles, which may therefore contain changes. The DOI will remain the same throughout.
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Nov 29, 2024 | 
onlinelibrary.wiley.com | Jinli Chen |Shenzhen Branch |Guangdong Laboratory |Dong Wang
Supporting Information Filename Description ins13476-sup-0001-SuppMat.docx1.7 MB Fig. S1 Cryo-EM mapping and AlphaFold-predicted structure of TcABCC-9C. Fig. S2 Docking analysis of avermectin and hexythiazox. Fig. S3 Reaction diagram of pyruvate-coupled ATPase assay. References , , , , , et al. (2024) Accurate structure prediction of biomolecular interactions with AlphaFold 3. Nature, 630, 493–500.
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Nov 26, 2024 | 
microbiologyresearch.org | Guangdong Laboratory |South Agricultural
Article metrics loading... /content/journal/ijsem/10.1099/ijsem.0.006550References Hesse C, Schulz F, Bull CT, Shaffer BT, Yan Q et al. Genome-based evolutionary history of Pseudomonas spp. Environ Microbiol 2018; 20:2142–2159 [View Article] [PubMed][Google Scholar] Peix A, Ramírez-Bahena M-H, Velázquez E. The current status on the taxonomy of Pseudomonas revisited: an update.
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Nov 22, 2024 | 
academic.oup.com | Shenzhen Branch |Guangdong Laboratory
Genome assembly errors can have a profound effect on downstream analyses. Collinearity-based Assembly Correction Tool (CATG) is designed to rectify these errors by leveraging collinearity information between the assembled genome and a reference genome. CATG provides a user-friendly interface for visualizing and manually correcting assembly errors. It supports various operations such as insertion, deletion, inversion, and swapping of contigs and chromosomes.
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Nov 11, 2024 | 
genomebiology.biomedcentral.com | Shenzhen Branch |Guangdong Laboratory
A total amount of 0.2 μg DNA of T cells per sample was used as input material for the DNA library preparations. Human PBMCs were provided by Milestone Biological Science & Technology (Shanghai, China). PBMCs were resuspended at 1 × 106 cells/mL in X-VIVOTM 15 Serum-free Hematopoietic Cell Medium (Lonza), supplemented with 10mM neutralized NAC (Sigma-Aldrich), and 10 ng/mL IL-7/IL-15. Briefly, the genomic DNA sample was fragmented by Covaris LE220R-plus (Covaris, USA) to a size of 350 bp.
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Sep 17, 2024 | 
onlinelibrary.wiley.com | Miner Deng |South Agricultural |Guangdong Laboratory |Zoonotic Diseases
1. Introduction Cholangitisis an important clinicalmanifestation of infections by many parasites, such as Cryptosporidium spp. in immunocompromised persons and liver trematodes (Opisthorchis spp., Clonorchis sinensis, and Fasciola hepatica) and cestodes (Echinococcus granulosus and E. multilocularis) in humans and animals in many parts of the world [1]. Despite its public and veterinary health significance, the pathogenesis of parasitic cholangitis is poorly understood.
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Aug 29, 2024 | 00321-0&sz=64)
cell.com | Shenzhen Branch |Guangdong Laboratory
Get full text accessLog in, subscribe or purchase for full access. References1. Smith, H.O. ∙ Hutchison, 3rd, C.A. ∙ Pfannkoch, C. ... Generating a synthetic genome by whole genome assembly: ϕX174 bacteriophage from synthetic oligonucleotidesProc. Natl. Acad. Sci. USA. 2003; 100:15440-154452. Cello, J. ∙ Paul, A.V. ∙ Wimmer, E. Chemical synthesis of poliovirus cDNA: generation of infectious virus in the absence of natural templateScience. 2002; 297:1016-10183.
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Aug 23, 2024 | 
onlinelibrary.wiley.com | Hongbing Liu |Shenzhen Branch |Guangdong Laboratory |Hang Zhao
INTRODUCTION The sedge species Eleocharis vivipara is highly regarded for its ornamental, ecological, and genetic research significance (Ueno, 2001; Baksh and Richards, 2006). This species exhibits distinct structural traits, such as its leafless habit with slender, linear, photosynthetic culms, setting it apart from other genera within the Cyperaceae and Poaceae families, and contributing to its ornamental appeal (Figure 1A). Ecologically, E.
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Aug 20, 2024 | 
parasitesandvectors.biomedcentral.com | South Agricultural |Guangdong Laboratory |Zoonotic Diseases
C57BL/6J (C57) and interferon gamma (IFN-γ) knockout (GKO) mice were used in this study. They were obtained from the Guangdong Medical Laboratory Animal Center (Guangzhou, China) and the Jackson Laboratory (Bar Harbor, ME, USA), respectively. For each experiment, mice were matched for sex and age, and were used at the age of 3–4 weeks. The Cryptosporidium parvum IIdA20G1-HLJ isolate was originally obtained from a dairy calf during a cryptosporidiosis outbreak [19].
