Håkan Olausson

Nov 4, 2024 | nature.com | Huasheng Yu |Saad S. Nagi |Dmitry Usoskin |Yizhou Hu |Otmane Bouchatta |Hanying Yan | +10 more

AbstractThe versatility of somatosensation arises from heterogeneous dorsal root ganglion (DRG) neurons. However, soma transcriptomes of individual human (h)DRG neurons—critical information to decipher their functions—are lacking due to technical difficulties. In this study, we isolated somata from individual hDRG neurons and conducted deep RNA sequencing (RNA-seq) to detect, on average, over 9,000 unique genes per neuron, and we identified 16 neuronal types.

Jul 21, 2024 | nature.com | Reinoud Kaldewaij |Andrea J. Capusan |Håkan Olausson

Correction to: Neuropsychopharmacology https://doi.org/10.1038/s41386-024-01906-2, published online 25 June 2024Due to a typesetting mistake, the funding information was incomplete. The Funding section has been corrected from “Open access funding provided by Linköping University” to “Open access funding provided by Linköping University.

Jun 24, 2024 | nature.com | Reinoud Kaldewaij |Andrea J. Capusan |Håkan Olausson

AbstractA coherent sense of self is crucial for social functioning and mental health. The N-methyl-D-aspartate antagonist ketamine induces short-term dissociative experiences and has therefore been used to model an altered state of self-perception. This randomized double-blind placebo-controlled cross-over study investigated the mechanisms for ketamine’s effects on the bodily sense of self in the context of affective touch.