Hannah M. Knochelmann

Nov 1, 2024 | jitc.bmj.com | Anna Cole |Hannah M. Knochelmann |Megan Wyatt |Megen C Wittling

http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial.

Oct 31, 2024 | jitc.bmj.com | Megan Wyatt |Hannah M. Knochelmann |Anna Cole |Megen C Wittling

http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial.

Jun 1, 2024 | jitc.bmj.com | Megen C Wittling |Hannah M. Knochelmann |Megan Wyatt |Anna Cole

MethodsThese studies were conducted using C57BL/6 and TRP-1 TCR transgenic mice (Rag−/− BWTRP-1 TCR) purchased from Jackson Laboratories. The TRP-1 TCR transgenic mice (Rag−/− BWTRP-1 TCR) are bred in-house at Emory University, while C57BL/6 mice were purchased from the Jackson Laboratory, and tumor experiments are conducted with mice ages 6–10 weeks.

Dec 18, 2023 | biorxiv.org | Hannah M. Knochelmann |Megan Wyatt |Anna Cole |Megen C Wittling

AbstractBackground: Mechanisms by which distinct methods of host preconditioning impact the efficacy of adoptively transferred antitumor T helper cells is unknown. Methods: CD4+ T cells with a transgenic TCR that recognize TRP-1 melanoma antigen were polarized to the T helper 17 (Th17) phenotype and then transferred into melanoma-bearing mice preconditioned with either total body irradiation or chemotherapy.