Henrik Grönberg

Nov 6, 2024 | nature.com | Joan Röhl |Johanna Schleutker |Kenneth Muir |Henrik Grönberg |Nora Pashayan |Demetrius Albanes | +20 more

AbstractGenetic variation at the 19q13.3 KLK locus is linked with prostate cancer susceptibility in men. The non-synonymous KLK3 single nucleotide polymorphism (SNP), rs17632542 (c.536 T > C; Ile163Thr-substitution in PSA) is associated with reduced prostate cancer risk, however, the functional relevance is unknown. Here, we identify that the SNP variant-induced change in PSA biochemical activity mediates prostate cancer pathogenesis.

Oct 7, 2024 | bpno.dk | Henrik Grönberg

oktober 2024 The first results from the ProBio study show that treatment with ARPI leads to longer PFS, but Henrik Grönberg predicts that there will be many larger publications and results from the study in the future. Få adgang Hvis du er læge, sygeplejerske eller anden sundhedsprofessionel kan du få adgang til hele artiklen ved at oprette en profil på BestPractice Nordic.

Oct 24, 2023 | bpno.dk | Henrik Grönberg

oktober 2023 At ESMO 2023 Henrik Grönberg, presented the ProBio study. He discussed the study design – which is described as an outcome-adaptive biomarker-driven platform trial – and the results of the study. The results demonstrate the superiority of new hormonal agents over taxanes in terms of progression-free survival and overall survival.