-
2 months ago | 
gut.bmj.com | Christopher Byrne |Giovanni Targher |Alessandro Mantovani |Herbert Tilg
FootnotesContributors GT, AM, CDB and HT contributed equally to the manuscript. GT is the guarantor for the overall content of the manuscript. Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors. Competing interests HT is an associate editor of the journal, and GT is an editorial board member of the journal. The authors do not have other potential conflicts of interest to disclose.
-
Jan 9, 2025 | 
nature.com | Herbert Tilg
The gut–liver axis is of crucial importance in health and disease. TM6SF2 is a genetic risk factor for metabolic dysfunction-associated steatotic liver disease. Zhang, Yu et al. reveal that intestinal TM6SF2 critically affects the gut–liver axis.
-
Nov 7, 2024 | 
nature.com | Herbert Tilg
AbstractAdipose tissue is an immunologically active organ that controls host physiology, partly through the release of mediators termed adipokines. In obesity, adipocytes and infiltrating leukocytes produce adipokines, which include the hormones adiponectin and leptin and cytokines such as tumour necrosis factor and IL-1β. These adipokines orchestrate immune responses that are collectively referred to as metabolic inflammation.
-
Jul 31, 2024 | 
nature.com | Timon E. Adolph |Herbert Tilg
Abstract‘Westernization’, which incorporates industrial, cultural and dietary trends, has paralleled the rise of noncommunicable diseases across the globe. Today, the Western-style diet emerges as a key stimulus for gut microbial vulnerability, chronic inflammation and chronic diseases, affecting mainly the cardiovascular system, systemic metabolism and the gut.
-
Jul 31, 2024 | nature.com | Timon E. Adolph |Herbert Tilg
Abstract‘Westernization’, which incorporates industrial, cultural and dietary trends, has paralleled the rise of noncommunicable diseases across the globe. Today, the Western-style diet emerges as a key stimulus for gut microbial vulnerability, chronic inflammation and chronic diseases, affecting mainly the cardiovascular system, systemic metabolism and the gut.
-
Jul 11, 2024 | 
gut.bmj.com | Alessandro Mantovani |Herbert Tilg |Giovanni Targher |Medizinische Universität Innsbruck
FGF-21 analogues for treatment of non-alcoholic steatohepatitis and fibrosis: a meta-analysis with fragility index of phase 2 randomised placebo-controlled trials Statistics from Altmetric.com Request Permissions If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.
-
May 22, 2024 | 
gut.bmj.com | Timon E. Adolph |Moritz Meyer |Almina Jukic |Herbert Tilg
ConclusionThe parallels and intricate link between metabolic disorders and IBD have emerged over the last decade by experimental and clinical studies alike. Current guidelines recommend treatment of obesity and metabolic disorders in patients with IBD as reported for patients without IBD. Many studies raise important questions for the future (box 3).
-
May 22, 2024 | gut.bmj.com | Timon E. Adolph |Moritz Meyer |Almina Jukic |Herbert Tilg
ConclusionThe parallels and intricate link between metabolic disorders and IBD have emerged over the last decade by experimental and clinical studies alike. Current guidelines recommend treatment of obesity and metabolic disorders in patients with IBD as reported for patients without IBD. Many studies raise important questions for the future (box 3).
-
May 22, 2024 | gut.bmj.com | Timon E. Adolph |Moritz Meyer |Almina Jukic |Herbert Tilg
ConclusionThe parallels and intricate link between metabolic disorders and IBD have emerged over the last decade by experimental and clinical studies alike. Current guidelines recommend treatment of obesity and metabolic disorders in patients with IBD as reported for patients without IBD. Many studies raise important questions for the future (box 3).
-
Apr 13, 2024 | 
mdpi.com | Moritz Meyer |Julian Schwärzler |Almina Jukic |Herbert Tilg
All articles published by MDPI are made immediately available worldwide under an open access license. No specialpermission is required to reuse all or part of the article published by MDPI, including figures and tables. Forarticles published under an open access Creative Common CC BY license, any part of the article may be reused withoutpermission provided that the original article is clearly cited. For more information, please refer tohttps://www.mdpi.com/openaccess.
