Hong Long Chen

Jan 3, 2025 | mdpi.com | Hong Long Chen

2.3.2. Based on the Theoretical Framework and the Actual Situation, the Hypothesis Is ProposedFirstly, the hypothesis is established from the aspect of external factors.

Dec 31, 2024 | mdpi.com | Hong Long Chen

This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessArticle by Xunmei Wu 1,2, Mengtao Han Dr. Mengtao Han received his B.S. and M.S. in Architecture from Huazhong University of Science and a [...] Dr. Mengtao Han received his B.S. and M.S. in Architecture from Huazhong University of Science and Technology in 2010 and 2013, respectively.

Mar 27, 2024 | elifesciences.org | Hong Long Chen |Lijun Sun |Lu Feng |Xue Han

eLife assessment This study provides valuable findings showing the production of IL-22 from intestinal ILC3 during intermittent fasting promotes beigeing of white adipose tissue. The authors provided solid data and mechanistic insight by which IL-22-derived from ILC3 directly induces beigeing.

Feb 23, 2024 | biorxiv.org | Hong Long Chen |Lijun Sun |Lu Feng |Xue Han

AbstractMechanism underlying the metabolic benefit of intermittent fasting remains largely unknown. Here, we reported that intermittent fasting promoted IL-22 production by type 3 innate lymphoid cells (ILC3s) and subsequent beigeing of subcutaneous white adipose tissue. Adoptive transfer of intestinal ILC3s increased beigeing of white adipose tissue in diet-induced-obese mice. Exogenous IL-22 significantly increased the beigeing of subcutaneous white adipose tissue.

Feb 7, 2024 | mdpi.com | Qing Chang |Hong Long Chen

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