Lijun Sun

Dec 9, 2024 | arxiv.org | Lijun Sun

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Nov 27, 2024 | arxiv.org | Qiang Wang |Lijun Sun

Mar 27, 2024 | elifesciences.org | Hong Long Chen |Lijun Sun |Lu Feng |Xue Han

eLife assessment This study provides valuable findings showing the production of IL-22 from intestinal ILC3 during intermittent fasting promotes beigeing of white adipose tissue. The authors provided solid data and mechanistic insight by which IL-22-derived from ILC3 directly induces beigeing.

Feb 23, 2024 | biorxiv.org | Hong Long Chen |Lijun Sun |Lu Feng |Xue Han

AbstractMechanism underlying the metabolic benefit of intermittent fasting remains largely unknown. Here, we reported that intermittent fasting promoted IL-22 production by type 3 innate lymphoid cells (ILC3s) and subsequent beigeing of subcutaneous white adipose tissue. Adoptive transfer of intestinal ILC3s increased beigeing of white adipose tissue in diet-induced-obese mice. Exogenous IL-22 significantly increased the beigeing of subcutaneous white adipose tissue.

Jan 16, 2024 | mdpi.com | Chen Wang |Dongfang Sun |Qi Deng |Lijun Sun

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