Articles

  • Nov 4, 2024 | onlinelibrary.wiley.com | Xuanyi Liu |Feng Ye |Yang Luo |Hongyan Fu

    Conflict of Interest The authors declare no conflict of interest. References 1, , Adv. Opt. Photonics 2016, 8, 465. 2, , IEEE Photonics Technol. Lett. 2000, 12, 1613. 3, , , , Appl. Opt. 2018, 57, 7410. 4, , , , , , , Electron. Lett. 1993, 29, 447. 5, , , Opt. Express 2010, 18, 15475. 6, , , , , , , Opt. Express 2016, 24, 9966. 7, , , , , , , Opt. Express 2005, 13, 9346. 8, , , , , , , Opt. Express 2020, 28, 29766. 9, , , , , in (CLEO). Conf.

  • Sep 10, 2024 | nature.com | Hongyan Fu |Zhaojun Wang |Tingting Zhao |Fan Wu |Yanan Zhang |Juan Chen | +7 more

    This study aimed to assess the potential of home monitoring using a monitoring application for the early prediction of acute exacerbations (AEs) in patients with fibrosing interstitial lung diseases (F-ILDs) by tracking symptoms, peripheral blood oxygen saturation (SpO2), and heart rate (HR). Data on symptoms, SpO2, and HR before and after a 1-min sit-to-stand test (1STST) were collected using an online home monitoring application. Symptoms were recorded at least 3 times a week, including cough intensity and frequency (Cough Assessment Test scale (COAT) score), breathlessness grade (modified Medical Research Council (mMRC) score), and SpO2 and HR before and after 1STST. Eighty-five patients with stable F-ILDs were enrolled. We observed a significant increase in COAT and mMRC scores, alongside a significant decrease in SpO2 before and after 1STST, 2 weeks before the first recorded AE. Furthermore, a combination of variables-an increase in COAT (≥ 4) and mMRC(≥ 1) scores, a decrease in SpO2 at rest (≥ 5%), and a decrease in SpO2 after 1STST (≥ 4%)- proved the most effective in predicting AE onset in patients with F-ILDs at 2 weeks before the first recorded AE. Home telemonitoring of symptoms, SpO2 holds potential value for early AE detection in patients with F-ILDs.

  • Jan 16, 2024 | nature.com | Xuanyi Liu |Hongyan Fu

    AbstractA highly efficient second-harmonic source is integrated into a silicon nitride microring resonator, unlocking the potential for advanced chip-scale devices such as miniaturized atomic clocks and fully integrated self-referenced microcombs. Second-harmonic generation (SHG) is a nonlinear optical process in which photons of one frequency are converted into photons with twice the frequency.

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