Fan Wu

Jan 9, 2025 | nature.com | Melissa Lumish |Saskia Hartner |Sasha Balkaran |Jonathan Bermeo |Simran Asawa |Asha Saxena | +12 more

Correction to: Nature https://doi.org/10.1038/s41586-024-08150-0 Published online 30 October 2024In the version of this article initially published, initials were used instead of the authors’ given names, and the second affiliation shown for Emmanouil Pappou (Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA) was incorrect. The names and affiliation have been amended in the HTML and PDF versions of the article.

Dec 31, 2024 | ift.onlinelibrary.wiley.com | Jingyu Gao |Fan Wu |Mingzhu Yan |Xuejiang Wang |Yu ZHANG |Yu Hsuan Peng | +3 more

Brown seaweed oligosaccharides (BSO) have demonstrated potential as nutraceuticals with cholesterol-lowering, anti-obesity, and anti-constipation properties. In this study, we initially examined how BSO impact body weight, blood lipid levels, and adipose tissue in a rat model of obesity induced by a high-fat diet. Our findings revealed that BSO administration significantly attenuated body weight gain, ameliorated dyslipidemia, and reduced visceral adiposity.

Oct 14, 2024 | tandfonline.com | Wei Yan |Fan Wu |Hui Wang |Zhuo Xu

ABSTRACTDiesel engines need to meet the higher emission requirement according to the Euro VI emission standards, and changes in the assembly tolerance of diesel engines will affect the consistency of nitrogen oxides(NOx) emissions. To study the influence of assembly tolerance on NOx emission, a heavy diesel engine was used as the research prototype. The combustion model of the diesel engine was simulated by the Converge software and calibrated with the bench test data.

Sep 30, 2024 | mdpi.com | Juan Du |Fan Wu

1. Introduction ∂ t u + u · ∇ u − Δ u + ∇ π = 0 , x ∈ R 3 , t > 0 ∇ · u = 0 , x ∈ R 3 , t > 0 u t = 0 = u 0 ( x ) , x ∈ R 3 , (1) where The Navier–Stokes equation (NSE for short) is one of the fundamental equations of fluid dynamics. The three-dimensional viscous incompressible NSE reads as u = ( u 1 , u 2 , u 3 ) —the velocity field—and π—the pressure—are the unknowns, and u 0 is the initial velocity field.

Sep 10, 2024 | nature.com | Hongyan Fu |Zhaojun Wang |Tingting Zhao |Fan Wu |Yanan Zhang |Juan Chen | +7 more

This study aimed to assess the potential of home monitoring using a monitoring application for the early prediction of acute exacerbations (AEs) in patients with fibrosing interstitial lung diseases (F-ILDs) by tracking symptoms, peripheral blood oxygen saturation (SpO2), and heart rate (HR). Data on symptoms, SpO2, and HR before and after a 1-min sit-to-stand test (1STST) were collected using an online home monitoring application. Symptoms were recorded at least 3 times a week, including cough intensity and frequency (Cough Assessment Test scale (COAT) score), breathlessness grade (modified Medical Research Council (mMRC) score), and SpO2 and HR before and after 1STST. Eighty-five patients with stable F-ILDs were enrolled. We observed a significant increase in COAT and mMRC scores, alongside a significant decrease in SpO2 before and after 1STST, 2 weeks before the first recorded AE. Furthermore, a combination of variables-an increase in COAT (≥ 4) and mMRC(≥ 1) scores, a decrease in SpO2 at rest (≥ 5%), and a decrease in SpO2 after 1STST (≥ 4%)- proved the most effective in predicting AE onset in patients with F-ILDs at 2 weeks before the first recorded AE. Home telemonitoring of symptoms, SpO2 holds potential value for early AE detection in patients with F-ILDs.