Zhaojun Wang

Sep 10, 2024 | nature.com | Hongyan Fu |Zhaojun Wang |Tingting Zhao |Fan Wu |Yanan Zhang |Juan Chen | +7 more

This study aimed to assess the potential of home monitoring using a monitoring application for the early prediction of acute exacerbations (AEs) in patients with fibrosing interstitial lung diseases (F-ILDs) by tracking symptoms, peripheral blood oxygen saturation (SpO2), and heart rate (HR). Data on symptoms, SpO2, and HR before and after a 1-min sit-to-stand test (1STST) were collected using an online home monitoring application. Symptoms were recorded at least 3 times a week, including cough intensity and frequency (Cough Assessment Test scale (COAT) score), breathlessness grade (modified Medical Research Council (mMRC) score), and SpO2 and HR before and after 1STST. Eighty-five patients with stable F-ILDs were enrolled. We observed a significant increase in COAT and mMRC scores, alongside a significant decrease in SpO2 before and after 1STST, 2 weeks before the first recorded AE. Furthermore, a combination of variables-an increase in COAT (≥ 4) and mMRC(≥ 1) scores, a decrease in SpO2 at rest (≥ 5%), and a decrease in SpO2 after 1STST (≥ 4%)- proved the most effective in predicting AE onset in patients with F-ILDs at 2 weeks before the first recorded AE. Home telemonitoring of symptoms, SpO2 holds potential value for early AE detection in patients with F-ILDs.

Jan 1, 2024 | nature.com | Zhaojun Wang

AbstractMast cells are phenotypically and functionally heterogeneous, and their state is possibly controlled by local microenvironment. Therefore, specific analyses are needed to understand whether mast cells function as powerful participants or dispensable bystanders in specific diseases.

Oct 26, 2023 | onlinelibrary.wiley.com | Junjun Wu |Lin Zhou |Hu Peng |Zhaojun Wang

Supporting Information Filename Description adma202304364-sup-0001-SuppMat.pdf2.4 MB Supporting Information adma202304364-sup-0002-MovieS1.mp41.8 MB Supplemental Movie 1 adma202304364-sup-0003-MovieS2.mp46 MB Supplemental Movie 2 adma202304364-sup-0004-MovieS3.mp45.5 MB Supplemental Movie 3

Feb 21, 2023 | mdpi.com | Yan Ji |Zhaojun Wang |Qian Deng |Jie Chen

Open AccessArticle byYan Ji 1, Zhaojun Wang 1,*, Qian Deng 1, Jie Chen 1, Zhiyong He 1, Maomao Zeng 1, Fang Qin 2 and Hongyang Pan 2,* 1State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China2International Joint Laboratory on Food Safety, Jiangnan University, Wuxi 214122, China*Authors to whom correspondence should be addressed.