houyu Zhang

Aug 19, 2024 | pubs.rsc.org | Tian Tian |Jiaqi Li |Dongxue Guo |houyu Zhang

Bridge-tuned through-space charge transfer for TADF and HLCT emissions Thermally activated delayed fluorescence (TADF) and hybridized local and charge transfer (HLCT) emitters represent two distinct yet highly efficient classes of electroluminescent materials. However, their designs are commonly independent due to their unique mechanisms for converting cold/hot triplet excitons into singlet excitons through the reverse intersystem crossing (RISC) process.

Mar 14, 2024 | elifesciences.org | Guangqin Wang |Yunpeng Gu |zhiyong Liu |houyu Zhang

eLife assessment In this valuable study, the authors explore regulatory cascades governing mammalian cochlear hair cell development and survival. They confirm previous studies that the transcription factors Pou4f3 and Gfi1 are necessary for hair cell survival and use compelling evidence to demonstrate that the RNA-binding protein gene RBM24 is regulated by Pou4f3, but not Gfi1.

Mar 12, 2024 | elifesciences.org | houyu Zhang |Carlos Ibanez |Meng Xie |Pablo Serratosa Luján

eLife assessment This study presents a valuable finding on the process of brown-to-white adipogenic transdifferentiation within the perirenal adipose depot. The evidence supporting the claims is convincing, although limited sequencing depth of single nuclei and lack of regulatory insights somewhat lessens the impact of these findings. The work will be of interest to adipose tissue biologists.

Oct 14, 2023 | biorxiv.org | houyu Zhang |Carlos Ibanez |Meng Xie

AbstractPerirenal adipose tissue (PRAT) is a unique visceral depot that contains a mixture of brown and white adipocytes. The origin and plasticity of such cellular heterogeneity remains unknown. Here, we combine single-nucleus RNA sequencing with genetic lineage tracing to reveal the existence of a distinct subpopulation of Ucp1-/Cidea+ adipocytes that arises from brown-to-white conversion during postnatal life in the peri-ureter region of mouse PRAT.