Huacui Chen

Aug 21, 2024 | biorxiv.org | Jocelyn Chen |Peng Xu |Wesley L. Cai |Huacui Chen

AbstractMetastasis is the major cause of cancer-related deaths. Emerging evidence has shown that epigenetic regulation plays a fundamental role in cancer metastasis. To better understand the epigenetic regulation of metastasis, we conducted an in vivo shRNA screen for vulnerabilities of brain metastasis and identified N-acetyltransferase 10 (NAT10) as a driver of brain metastasis.